Plasma Cytokine Profiles in Subjects with High-Functioning Autism Spectrum Disorders

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Plasma Cytokine Profiles in Subjects with High-Functioning Autism Spectrum Disorders

BACKGROUND Accumulating evidence suggests that dysregulation of the immune system is involved in the pathophysiology of autism spectrum disorders (ASD). The aim of the study was to explore immunological markers in peripheral plasma samples from non-medicated subjects with high-functioning ASD. METHODOLOGY/PRINCIPAL FINDINGS A multiplex assay for cytokines and chemokines was applied to plasma ...

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Although a small number of studies have investigated sex differences in the associated features of high-functioning autism spectrum disorders (HFASDs), they have failed to provide consistent findings. We sought to examine sex differences in 5–9-year-old females and males with HFASDs within a narrow range of ages before adolescence in order to identify the noticeable autistic profile of females ...

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Previous studies have shown that immunological factors are involved in the pathogenesis of autism spectrum disorders (ASDs). However, this research has been conducted almost exclusively in Western contexts, and only a handful of studies on immune measures have been conducted in Asian populations, such as Chinese populations. The present study examined whether immunological abnormalities are ass...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2011

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0020470